Shaista Ali, Samia Sarwar, Ifra Saeed.
Changes in Arrangement of Chondrons in Radial Zone of Ageing Male Human Articular Cartilage.
J Rawal Med Coll Jan ;20(4):317-9.

Background:To study the variation in arrangement of chondrons in radial zone of male human articular cartilage.Methods:Forty samples of articular cartilage from male dead bodies ageing between 21 –60 years were collected and divided into four groups. After tissue processing and cutting, H&E and special staining with Masson’s Trichrome was done and arrangement of chondrons was noted. Results:With advancing age the arrangements of chondrons in radial zone of group A, B and C was in short columns while in group D, the arrangement was disturbed. The chondrons were observed in pairs and clusters.Conclusion:In ageing articular cartilage the arrangements of chondrons in radial zone of articular cartilage is alteredleading to osteoarthritis that makes it focus of intense study for preventive measures and treatment.

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