I Sheraz M Ali, Sofia Ahmed, Iqbal Ahmad.
Developments in the Clinical and Food Analysis of Vitamin-C.
Baqai J Health Sci Jan ;10(2):19-24.

Vitamin C (ascorbic acid) is a water-soluble vitamin that is necessary for the prevention and cure of the deficiency disease scurvy. It plays an important role as redox cofactor and catalyst in a broad array of biochemical reactions and processes. The redox behavior of ascorbic acid is the basis of most of the analytical methods used for its determination. The various methods developed for the determination of ascorbic acid in biological samples and food materials include spectrophotometric methods, fluorimetric methods, mass spectrometric methods, chromatographic methods and enzymatic methods. The high-performance liquid chromatographic methods using different detection systems are highly specific and sensitive for the determination of ascorbic acid and related compounds such as dehydroascorbic and isoascorbic acid in biological samples.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com