Muhammad Ali Sheraz, Sofia Ahmed, Saif-ur Rehman Khattak, Iqbal Ahmad.
Mechanism of Bacterial Resistance.
Baqai J Health Sci Jan ;12(1):35-40.

The antibiotic resistance in microorganisms is a worldwide problem that results due to chemotherapy of microbial diseases. The appearance of gradual resistance shows that a single antibiotic loses its effectiveness with the laps of time against microorganisms. Bacteria may develop resistance intrinsically or acquire it either vertically or horizontally. This review highlights the mechanisms involved in the resistance development of bacterial species against different classes of widely used antibiotics.

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