Adeel Arsalan, Arif Sabah, Iqbal Ahmad, Syed Baquir Shayam, Syed Imran Ali.
The Role of Antiseptics in Surgery.
Baqai J Health Sci Jan ;13(2):47-54.

Surgical site infection (SSIs) are one of the most frequent causes of nosocomial infections which not only increase the stay in the hospitals but also burden the patient financially. Skin acts as a barrier in the invasion of microbes from environment but on injury, the major source of infections could be normal flora on the skin. Antiseptic agents (ASAs) are applied on the skin as well as on the mucous membrane of minimize the chances of infection. ASAs should have a prolonged action to be more beneficial. A number of factors are involved in the prevention of SSIs. It been established that the use of sterile antiseptics not only reduces the source of infections but also improves patient’s condition. A number of ASAs alone or as admixtures are commercially available and provide complete or partial eradication of microbes. ASAs like alcohols, chlorohexadiene, iodine/iodophor, xylenol, triclosan and octenidine are still commonly used developed countries.

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