Riffat Sultana, Anjum Humayun, Nargis Parveen, Shamim Alam.
Lipoprotein Abnormalities And Body Mass Index Differences In Type 2 Diabetic Postmenopausal Women In Tertiary Care Hospitals Of Peshawar.
Esculapio J Services Inst Med Sci Jan ;7(1):20-5.

Objective: To detect serum lipoprotein abnormalities and Body Mass Index differences in type 2 diabetic post menopausal women compared to controls. Material & Methods: This case control studywas conducted at Tertiary care hospitals of Peshawar, that is Hayatabad Medical Complex, Khyber Teaching Hospital, and Lady Reading Hospital over a period of two years i.e., from July 2005 to July 2008.One hundred and fifty diagnosed diabetes type 2 post menopausal females compared with fifty non diabetic post menopausal healthy controls were included. Determination of glucose, total cholesterol, high density lipoprotein cholesterol were assessed by enzymatic lab technique (Elitech) using micro lab 200 (Merck), and low density lipoprotein cholesterol was determined by Friedewald formula. Results: The results indicated highly significant difference between the biochemical indices of cases and controls which included elevated levels of LDL-C (p=0. 001), reduced levels of HDL-C (p=0.001) and triglycerides (TG) above the target levels (p=.000). Body Mass Index showed significant change in diabetic postmenopausal females as compared to controls. (p<0.015). Conclusion: Dyslipidemias in post menopausal diabetic females are more prevalent. Lipoprotein abnormalities are a risk factor for cardiovascular diseases which becomes more prevalent with the loss of estrogens and the decrease in High density lipoprotein (HDL) cholesterol levels that occurs concurrently with menopause.

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