Zahid Hussain Shah, Sajid Abaidullah, Muhammad Imran, Khurram Saleem, Zafar Niaz, Aurangzeb Afzal, Zunaira Arshad, Mobeen Riaz, Lal Badshah, Sheeraz Saleem.
Frequency Of Restrictive Pulmonary Dysfunction In Type-1 & Type-2 Diabetes Mellitus.
Esculapio J Services Inst Med Sci Jan ;7(2):26-31.

Objective: To determine the frequency of restrictive pulmonary dysfunction in type 1 & type 2 diabetic patients and to measure the severity of pulmonary dysfunction. Material & Methods: This study included 255 patients of type I and type II diabetes who had followed up in the out patient departments of Pulmonology and Medicine in Mayo Hospital, Lahore. Forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were measured using standard spirometry. Results: Mean age was 47.26±19.076 years. 230 (90.2%) were males and 25 (9.8%) were females. 58 (22.7%) were type 1 diabetics and 197 (77.3%) were type 2 diabetics. 37 (14.5%) had restrictive pathology, 6 (2.4%) had obstructive pathology and 212 (83.1%) had normal lung function tests. 35 (13.7%) had mild restrictive dysfunction and 2 (0.8%) had moderate restrictive lung dysfunction. Conclusion: These data support the notion that the lung is a target organ for diabetic injury. Additional research is required to identify pathophysiologic mechanisms and to determine clinical significance.

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