Lubna Riaz Dar, Shaazia Rasul.
Long Term Outcome of Patients with Endometriosis on Medical Treatment.
Esculapio J Services Inst Med Sci Jan ;8(3):140-2.

Objective: To evaluate long term outcome of patients with endometriosis on medical treatment (OCP's, progestin, clomiphene citrate according to need of patients), in terms of symptomatic relief, successful conception, recurrence & treatment failure. Material & Methods: This quasi experimental study was conducted in Shalamar Hospital Lahore. All patients who had confirmed diagnosis of endometriosis by laparoscopy or by laparotomy were included in the study after informed consent. Type of medical management was decided according to the need of the patients. The patients who did not want to conceive were given medical treatment in the form of combined oral contraceptive pills or progesterone. Patients who wanted to conceive, were given clomiphene citrate. Patients were followed up for 1 to 9 years. Study outcome was expressed in terms of symptomatic relief, pregnancy, recurrence and treatment failure. Data was analyzed using SPSS version 16. Results: Initially, there were 94 patients who had confirmed endometriosis and were included in the study. Out of these,18 patients lost follow up, and were excluded from study. The mean age of these patients was 25±4.73 years and 50 percent presented with pelvic pain and 36% with infertility. They were followed for 1-9 years. The mean duration of follow up was 4.37±2.29 years. 61.8% cases became symptom free, 15.8% conceived successfully, whereas 9.2% had persistence of pain. 11.8% had recurrence rate over 12-14 months after discontinuation of medical treatment. Conclusion: Long term follow up of patients with endometriosis showed that medical treatment of endometriosis with COCPs, progestogens, and clomiphene citrate has promising results with less then 20% cases requiring other modes of treatment.

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