Ikram-ur Rahim, Omar Ahsan.
Frequency of Helicobacter Pylori (H. Pylori) in Patients of Acid Peptic Disease.
Esculapio J Services Inst Med Sci Jan ;8(4):163-6.

Objective: To find the frequency of H. pylori positivity in patients of acid peptic disease. Material & Methods: This descriptive study was conducted in Akhtar Saeed Trust Teaching Hospital, Lahore from September 2011 to December 2011. History and physical examination was recorded and oesophagogastroduodenoscopy (OGD) was done. Findings were noted and antral biopsy samples preserved in 10% formalin were sent for histopathological examination for the presence of H. pylori. Results: Fifty patients with mean age 41 years were included. Most of them were males .H. pylori was positive in 72% on histopathology report and in this 82% were males and 46% belonged to lower socioeconomic group. 57% were positive for H. pylori in NSAIDs users. Most frequent complaint was epigastric pain (92%) and 80% had nausea and vomiting. Endoscopy showed gastritis in 54% and duodenitis / duodenal ulcer in 14%. Conclusion: High frequency of H. pylori in patients of acid peptic disease suggest that it is the most common cause especially in middle aged and lower socioeconomic group males. It should be promptly diagnosed and treated.

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