Siddique Ahmad, Yousaf Jan, Waqas, Shaukat Hussain, Aurangzeb Khan.
Role of Prophylactic Antibiotic in Prevention of Wound Infections following Lichtenstein Inguinal Hernioplasty.
Ophthalmol Update Jan ;12(3):240-5.

Background: Inguinal hernia is one of commonest condition encountered in clinical practice. Mesh repair is becoming the most popular technique for inguinal hernia repair. The use of antibiotic prophylaxis during Lichtenstein inguinal hernia surgery is controversial. Objective: To determine the role of single dose intravenous antibiotic prophylaxis over no antibiotic prophylaxis in the prevention of wound infection following Lichtenstein inguinal hernioplasty in patients with no other co-morbid conditions. Methods: This prospective study was conducted at surgical unit Hayatabad Medical Complex Peshawar from March 2010 to August 2011. A total of first consecutive 150 cases of inguinal hernia were randomized to receive 1.5 gram intravenous cefuroxime (group-A) before the incision or an equal volume of placebo (group-B). All patients underwent Lichtenstein inguinal hernioplasty with prolene mesh electively under spinal anaesthesia . Results: A total of 150 patients were included in the study. Minimum age of patients in this study was 20 years and maximum 75 years with a mean of 44.06 in group A and 44.84 in group B. The total number of wound infections was 7 (4.0%), 2 (2.66%) in the group A and 6 (8%) in group B. Conclusion: We conclude that there is no benefit of intravenous single dose antibiotic prophylaxis in the prevention of wound infection following Lichtenstein inguinal hernioplasty in patients with no other co-morbid conditions.

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