Mubashir Rehman, Imran Ahmad, Bilal Bashir, Mohammad Zeeshan Tahir, Asif Iqbal, Asim Ali Shah.
Effectiveness of Ketorolac Tromethamine in reducing Post-operative Inflammation after Phacoemulsification and Intra-ocular Lens Implantation.
Ophthalmol Update Jan ;12(4):262-6.

Objective: To determine the efficacy of Ketorolac tromethamine in reducing postoperative inflammation after phacoemulsification and intra-ocular lens implantation in terms of grades of anterior chamber cells and grades of aqueous flare. Study design: It was a descriptive cross sectional study. Place and duration of study: The study was conducted at Eye ?B? Unit Khyber Teaching Hospital Peshawar from March 2009 to March 2010. Patients and methods: This study was carried out on 59 patients. An informed consent was obtained from all patients for including the patients in this study and using their data in the study. Examination included detailed anterior segment examination with slit lamp and fundus examination. All cases underwent phacoemulsification with intraocular lens implantation by same surgeon. Next morning grades of AC cells and grades of aqueous flare were examined on slit lamp biomicroscopy with a 2 mm long and 1 mm wide slit beam with maximal light intensity. Patient were started on Ketorolac tromethamine (0.5%) eye drops four times per day along with Tobramycin (0.3 %) eye drops four times per day. Follow up was at 7th and 30th postoperative days and at each visit grades of AC cells and grades of aqueous flare were examined on slit lamp biomicroscopy with same parameters as on 1st postoperative day. Results: The mean age was 62.50 ± 5.51 years. The male to female ratio was 1.26:1. On first post-operative day before starting the topical drops, majority of the patients had moderate degree of inflammation in the anterior chamber. Flare in the anterior chamber was faint in a few cases. On 7th postoperative day inflammation in the anterior chamber was much reduced. On 30th postoperative day inflammation was greatly reduced, only 11 patients had 1-5 cells in the anterior chamber, while the remaining had less than 1 cell. Flare got resolved in all cases. Conclusion: Ketorolac tromethamine is effective for control of postoperative inflammation after phacoemulsification with intra-ocular lens implantation. We recommend the use of Ketorolac Tromethamine after phacoemulsification surgery.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com