Omar Ilyas, Mubashir Rehman, Farooq Khan, Mohammad Sajid Khan, Sadia Sethi.
Mean Rise of IOP after IOL Implantation using 2% Hydroxypropyle Methylcellulose (HPMC) & Omar Ilyas 1% Sodium Hyaluronate (NAHA) Viscoelastics.
Ophthalmol Update Jan ;13(3):148-51.

Objective: To compare mean intraocular pressure rise after phacoemulsification with implantation of intraocular lens using 2% HPMC and 1% NaHa as viscoelastics. Study design: Randomized control trial. Place and duration of study: Ophthalmology Department, Khyber Teaching Hospital Peshawar from 1st August 2013 to 1st January 2014. Patients and methods: A detailed slit lamp examination was performed in all patients to look for any signs of intraocular inflammation or evidence of previous intraocular surgery. Those who fit the inclusion criteria were then randomly allocated into 2 groups. One group had been receiving 1% sodium hyaluronate as viscoelastic while second group 2% hydroxypropyle methylcellulose as viscoelastic. All surgeries were done by a single ophthalmologist. IOP was measured by the same ophthalmologist 1 day prior to surgery, then 1 day post operatively using Goldman applanation tonometer. Results: Mean age in Group A was 62 year with standard deviation ± 2.06, while in Group B was 64 year with standard deviation ± 2.87. In Group A 60% patients were male and 40% patients were female, while in Group B 57% patients were male and 43% patients were female. The mean rise of IOP in Group A was 4.36 ± 2.02 mmHg while the mean rise of IOP in Group B was 3.02± 2.36 mmHg. Conclusion: Our study concluded that Sodium Hyaluronate causes significantly higher increase in intraocular pressure in early post-operative period after cataract surgery inspite of maximum aspiration of viscoelastic substance from the eye following phacoemulsification surgery.

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