Imran Ahmad, Mubashir Rehman, Jehanzeb Khan, Zeeshan Tahir.
Comparison of Efficacy of Olopatidine Hydrochloride 0.1% & Ketotifen Fumarate 0.025% in Vernal Keratoconjunctivitis.
Ophthalmol Update Jan ;13(4):254-7.

To compare the efficacy of Olopatidine Hydrochloride 0.1% and Ketotifen fumarate 0.025% in vernal kertoconjunctivitis. Study design: Randomized control trials. Material & Methods: The study was conducted in the Out Patient Department of Hayatabad Medical Complex, Peshawar from May 2014 to May 2015. A total of 110 patients were divided into two groups of 55 patients each. Group ?A? were given topical Olopatidine Hydrochloride 0.1% twice a day whereas group ?B? were given Ketotifen Fumarate 0.025% three times a day. Patients were followed at week 1,2 and after 4 weeks to check for the improvement of symptoms. Result: 110 patients were included in the study and were divided into two groups of 55 patients each. Age range was from 3-16 years with a mean age of 8.73+3.64. Olopatidine Hydrochloride provide better relief of symptoms of itching, watering, redness and burning than Ketotifen Fumarate (p<0.05) in patients with VKC. Conclusion: Olopatidine Hydrochloride 0.1% is more efficacious than Ketotifen Fumarate 0.025% for symptomatic improvement in patients with VKC.

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