Talha Mahmud.
Adjunct Prednisolone Versus Anti Tuberculous Drugs Alone for Treatment of Tuberculous Pleurisy.
Proceeding Shaikh Zayed Postgrad Med Comp Jan ;24(1):51-4.

To determine the effect of adjunct prednisolone therapy, a randomized controlled trial was conducted involving 46 hospitalized patients having biopsy proven tuberculous pleurisy and were followed till the end of treatment. Patients were divided into two groups; one group was treated with standard anti tuberculous treatment while the other (group 2) was assigned adjunct prednisolone with anti tuberculous drugs. Fever and constitutional symptoms disappeared faster in group 2 (P value <0.001). After one month, there was a significantly greater reduction in the size of pleural effusion in group receiving adjunct prednisolone, but after 4 and 8 months the difference was not statistically significant. It was concluded that adjunct prednisolone alleviates symptoms and effusion earlier than anti tuberculous drugs alone but does not reduce the development of pleural thickening.

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