Shafique Ahmad, Faisal Ehsan, Muhammad Fahim, Muhammad Ramzan, Saulat Sarfraz, Mubashir Ejaz.
MDCT Contrast Enhancement Patterns of HCC.
Proceeding Shaikh Zayed Postgrad Med Comp Jan ;24(1):1-8.

Hepatocellular Carcinoma (HCC) ?responsible for a large proportion of cancer deaths worldwide? is frequently diagnosed after the development of clinical deterioration with poor survival. Triple phase CT scan enables good characterization and diagnosis even at an early stage and could improve survival. Objectives: To describe the frequency of (Heterogonous Mosaic) enhancement pattern of Hepatocellular carcinoma in cirrhotic patients on triple phase MultiDetector CT. Study Design: Descriptive Case series. Material & Methods: Study was performed in Radiology Department of FPGMI / Shaikh Zayed Hospital Lahore from September 30 2008 to March 30 2009. Sixty cirrhotic patients with ultrasound and histopathological evidence of Hepatocellular cancer underwent Triple phase contrast enhanced CT. Results: In sixty patients, 110 lesions detected. Eighty one (73.6%) of these were heterogeneous in appearance, while 55.5% of these were hyperattenuating as well. Seventy five (61/81) percent heterogeneous lesions showed mosaic pattern of enhancement. Twenty nine lesions (26.4%) were homogenous and 89% of these were hyperattenuating. Conclusion: Majority of the hepatocellular carcinoma lesions appear as heterogeneous and hyperattenuating. Mosaic internal contrast distribution is the leading pattern in these nodular lesions followed by ring enhancement.

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