Sarah A Zafar, Naveed Ahmad Qureshi, Arif Hayat Khan Pathan, Nadeem Qureshi, Fareeha Ambreen.
Surgical and Visual Outcomes of Retinal Detachment Surgery in Eyes with Chorio-Retinal Coloboma.
Pak Armed Forces Med J Jan ;66(6):795-9.

Objective: To evaluate the anatomical and visual outcome of surgical management of retinal detachment associated with chorio-retinal coloboma. Study Design: Prospective interventional case series Place and Duration of Study: This study was conducted at Al-Shifa Trust Eye Hospital Rawalpindi from Jan 2012 to Dec 2013. Material and Methods: Twenty one eyes (21 patients) that underwent surgery for retinal detachment associated with chorio-retinal colobomas were selected. Evaluation was done on the basis of type of intervention, final visual acuity and anatomical outcome and complications. Out of 21, 19(90.47%) eyes underwent pars plana vitrectomy with silicone oil (SO) and 2(9.52%) underwent primary scleral buckling surgery. SO was removed in 9 (47.36%) eyes at final follow up. Encircling band was placed in 12 (63.15%) eyes based on peroperative judgment of surgeon. intra-operative lensectomy was performed in 6 (28.57%) eyes. the main outcome measures were retinal re-attachment and visual recovery. Statistical analysis was performed using "IBM statistical package for social sciences (SPSS) Statistics" (version 17.0, Chicago, Illinois, USA). Qualitative variables were described using percentage; quantitative data were defined using mean ± standard deviation. the pre op and post op frequency of best corrected visual acuity (BCVA) was compared using Wilcoxan Signed Ranks Test. Confidence interval was 95% (level of significance p<0.05). Results: the mean number of operations per eye were 1.57± 0.74; mean follow-up was 13.1 months (range 12-18). the retina remained attached in 18 eyes (85.71%) at final follow-up. the post op BCVA improved significantly as compared to pre op BCVA (p< 0.01). Mean pre op BCVA was counting fingers (CF) and mean post op value of BCVA was 3/60. Conclusion: Pars plana vitrectomy along with silicon oil tamponade for retinal detachment related to choroiretinal coloboma improves the long-term anatomical outcome however no significant improvement in visual acuity was observed.

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