Irum Masood, Haris Rasheed, Irfan Amjad Lutf, Ahmed Raheem.
A pre-operative diagnostic dilemma and incidental prevalence in histopathology: Retrospective analysis of gallbladder tuberculosis.
Pak J Surg Jan ;33(1):79-82.

Background: Tuberculosis of the gallbladder is an occasional and able to cured entity. Preoperative diagnosis is a great challenging task while disease has non pathognomonic clinically and radiologically. Tuberculosis of the gallbladder is still made difficult with the gallbladder malignancy and some other gallbladder lesions. Histopathology can establish the right diagnosis of this isolated tuberculous infection of the gallbladder. Our study focus is to assess the frequency rate and pre-operative clinical pathognomonic for accurate diagnosis. Methods: Data searched retrospectively and reviewed patient’s record from January 2011 to June 2016 for tuberculosis of the gallbladder. Single center study conducted in Ziauddin University and hospital Karachi. In five years of period we had three cases of tuberculosis of the gallbladder. Result: Retrospective analysis showed incidentally three (0.16%) cases of tuberculosis of the gallbladder out of 1,765 gallbladder specimen after cholecystectmy. Total female was 1,255(71.1%) and male was 510(28.8%). Female and male ratio was 1:0.4. All three (100%) patients of gallbladder tuberculosis were female with history of recurrent right upper abdominal pain, fever, nausea, vomiting and weight loss. Laparoscopic cholecystectomy performed. Diagnosis was made on histopathology. Conclusion: There is no indicative sign and symptoms for preoperative diagnosis of tuberculosis of the gallbladder, usually depends on histopathology. For that reason all specimens of the gallbladder should be sent for histopathology to exhibit tuberculosis of the gallbladder in indigenous places. In spite of that post-operative proof is a pronounced catastrophe of diagnosis if acalculous cholecystitis, as a disease is treatable medically and surgery is inevitable.

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