Muhammad Yahya, Urwah Inam, Masood Raza Khan.
Incidence and management of priapism in sickle cell disease:A study from local hospital at south west Saudi Arabia.
Pak J Surg Jan ;33(1):20-4.

Objectives: To review the incidence, clinical presentation and management of sickle cell disease patients presenting with priapism. Material and methods: A prospective analysis of data base of total 212 male patients with sickle cell disease (43 patients) presented with priapism was performed. All data was transferred into a structured questionnaire which included patient’s demographic features, treatment given, duration of hospital stay and outcomes. The SPSS version 19 was used for statistical analysis. Results: Out of 212 male patients with sickle cell disease 43 (20.3%) male patients complaints of priapism. 27 patients came in emergency and they were admitted and given treatment and other 16 complain in OPD that they experience priapism. 5 patients (11.6%) know about priapism as a complication of sickle cell disease. All patients who came in emergency due to priapism were admitted and given initial treatment which consisted of intravenous fluid and aspiration/irrigation with normal saline. 5 patients were irrigated with dilute epinephrine (Adrenaline 1:1,000,000) Oral etilefrine therapy was prescribed for adults and children over 12 years of age. The self-administered intracavernous injection (SICI) technique was used in 7 patients who were very conscious about their sexual ability and impotence. Conclusion: Priapism is common in patients with sickle cell disease mostly in age group 20 to 25 years. It carries a significant role in impotence. It can be prevented by conveying knowledge to patients with sickle cell disease about priapism, appropriate diagnosis and prompt treatment. It has been suggested that with appropriate treatment preservation of potency can be achieved.

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