Salahuddin, Arifullah, Najma, Mehreen.
Risk assessment model of rural and urban breast cancer patients of Khyber Pakhtunkhwa province, Pakistan.
Pak J Med Res Jan ;57(2):71-6.

Background: Adult females are usually affected by the most common category of cancer known as the cancer of the breast. Objectives: To assess various risk factors leading to high incidence of women breast cancer, in urban-rural regions of the Khyber Pakhtunkhwa (KPK) province. Patients and Methods: Total of 500 patients were enrolled for the study visiting the cancer hospital, Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar. Among them, 270 were breast cancer patients. Logistic regression models were estimated through the backward elimination procedure to determine the risk factors of breast cancer. Results: Factors responsible were menopausal status, reproductive status as well as the interaction of family history and diet were the significant risk factors of rural regions. In an urban region, menopausal status and the interaction of breast feeding and diet were the significant risk factors. Conclusion: This study concludes that reproductive, menopausal status, along with family history, diet and the joint effects of breast feeding were the significant risk factors. Our recommendation from this study was that, the breastfeeding is a precautionary measure against breast cancer. It is, therefore, suggested that mothers, particularly in urban areas, should be encouraged to feed their children by breast feeding. Key words: Breast cancer, risk factors, backward elimination, brown test, logistic regression, urban and rural regions.

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