Ashok Kumar, Ajeet Kumar, Syeda Urooj Riaz, Rajesh Kumar, Muhammad Ishaq Ghauri, Naresh Kumar Setlani.
Child-Pugh Score Predicts Mortality Better than Model of End Stage Liver Disease: a study in a Tertiary Care Hospital in the Periphery of Karachi.
Ann Abbasi Shaheed Hosp Karachi Med Dent Coll Jan ;23(03):130-5.

Objective: To observe the scores of the model of end-stage liver diseaseand Child-Pugh (CP) scores on hospital admission in patients of cirrhosis. Methods: A cross-sectional study, in 6 months from September 17th to March 18th, using non-probability convenience sampling was conducted, in which we inducted 165 patients with diagnosed cirrhotic liver disease in aninpatient department. We noted the demographics and staged the patient for chronic liver disease according to Child-Turcotte-Pugh classification using ascites, encephalopathy, prothrombin time, serum albumin and serum bilirubin levels and compared it with MELD (Model for End-Stage Liver Disease) score using serum bilirubin, creatinine and change in INR. We predicted the outcome of patient according to both scores. Results: Out of 165 patients, 127 (76.96%, 84 males and 43 females) patients improved, while 38 (23.04%, 29 males and 9 females) patients expired. Correlation of CP and MELD scores was done by Pearson's bivariate correlation test and it gave the correlation coefficient of 0.626 with highly significant value of p<0.0001. The area under curve (AUC) was slightly more for CP (0.961) as compared to MELD (0.911). Conclusion: The MELD score compared to the CP score does not appear to offer a clear advantage in predicting mortality in patients with decompensated cirrhosis, but comparatively CP score performed better than the MELD with significantly higher AUC.

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