Sumaira Mehreen, Mazhar Ali Khan, Anila Basit, Afsar Khan, Nadia Ashiq, Arshad Javaid.
Frequency of Depression in Multidrug-Resistant Tuberculosis patients: an Experience from a Tertiary Care Hospital.
Pak J Chest Med Jan ;21(4):149-54.

Background: Both depression and Multi-drug resistant tuberculosis (MDRTB) are global public health problems that have a substantial impact on human health. However, depressive state among MDR-TB patients has not been well investigated in Pakistan. Objective: To find out the frequency of depression at baseline (at the time of registration) in currently diagnosed MDR-TB patients and the emergence of depression during MDR-TB treatment in registered MDR-TB patients in PMDT. Design: The longitudinal study was conducted at PMDT centre, Lady Reading st Hospital Peshawar (LRH) on patients enrolled for MDR-TB treatment from 1 th May 2012 to 30 August 2013. A total of 213 patients were included in this study. All newly diagnosed MDR-TB patients at the time of registration and on every follow up. Result: The total of 213 MDR-TB patients were recruited for the study. Out of 213 registered patients, 139 (65.5%) had depression at baseline. At the end of st nd 1 quarter, only 47 (33.81%) out of 139 still had depression and at the end of 2 quarter this number further decreased to 35 (15.10%). While the emergence of st nd depression was 36% at the end of both 1 and 2 quarter.

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