Mohammad Sajjad Khattak, Mohammad Akram Khattak, Sania Tanveer Khattak.
Frequency of Metaplastic Change in Benign Endometrial Curettage Specimen and its Histological Variants.
J Islamic Int Med Coll Jan ;12(1):35-8.

Objective: The objective of this study was to see the frequency and histological variants of endometrial metaplastic changes in benign endometrial curettage. Study Design: Cross sectional descriptive study. Place and Duration of Study: The study was conducted at Pathology department of Bannu Medical College. The st st duration was five years. From January 1 , 2011 to December 31 , 2015. Materials and Methods:In this study a total of 530 endometrial curettage specimen were analysed. All the data was collected during these five years from Pathology department register and the author was actively involved in examination and histopathology reporting. All benign endometrial curettage specimen from both pre and post-menopausal age were included. Autolysed, malignant and insufficient biopsy specimen were not included. A minimum of one and maximum of three blocks were prepared. Two to four 5 micron thick sections were taken, stained with H&E and PAS where required. Slides prepared were mounted and reported by Histopathologist (Author). The data was analysed in Statistical Package for Social Sciences (SPSS) version 20 for frequencies with percentages and mean with standered deviation. Results: A total of 530 endometrial samples were collected in this study with mean age of 33.65 years and age range was from 21 to 63 years. The incidence of endometrial metaplasia was 4.90% amongst 530 endometrial samples. The metaplastic changes in order of frequency were tubal metaplasia followed by squamous metaplasia, clear cell metaplasia, ciliated cell metaplasia and mucinous metaplasia. Conclusion: Endometrial metaplasia is a recognized histological entity in endometrial curettage specimen with variable histological presentation. In this study tubal metaplasia was the commonest metaplasia followed by squamous metaplasia.

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