Moazzam Ali Naqvi, Abdul Sattar, Syed Asif Ali, Muhammad Asif Iqbal, Manoj Shrestha.
Association Of Left Ventricle Diastolic Dysfunction (LVDD) With Uncontrolled Hypertension.
J Cardiovascular Dis Jan ;14(2):28-32.

BACKGROUND:Hypertension is a chronic medical condition with multisystem involvement. It usually remains asymptomatic for long time and can have sudden catastrophic consequences. Cardiac involvement in hypertension is a well known phenomenon resulting in a wide range of cardiac pathologies that varies from left ventricular hypertrophy to diastolic heart failure. Left ventricular diastolic dysfunction (LVDD) is usually the earliest cardiac manifestation of hypertension which can be detected by echocardiogram. OBJECTIVE: To determine the association between LVDD and uncontrolled hypertension. MATERIAL & METHODS: This case control study was conducted at department of cardiology, Punjab Institute of Cardiology, Lahore from 24 Nov 2016 to 23 May 2017. One hundred and sixty patients fulfilling the inclusion criteria were enrolled. The respondents were divided into two groups; cases with uncontrolled hypertension and control with controlled hypertension. Blood pressure was noted and Echocardiography was done. LVDD was measured using the standard parameters. RESULTS: The mean age of cases group was 44.71±13.68 years and in control group it was 47±13.68 years. Out of 160 patients, LVDD was found in 71(44.38%) patients : 57 in uncontrolled hypertension group and 14 in controlled hypertension group p<0.0001. Age (> 50 years) and duration of hypertension (> 12 months) were other predictors of LVDD. CONCLUSION: LVDD is more common in patients with uncontrolled hypertension then in patients with well controlled hypertension. KEYWORDS: Left ventricular

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