Warda Sattar, Shazia Kadri, Rab Nawaz.
Spinal Arteriovenous Metameric Syndrome (SAMS) / COBB Syndrome.
Pak J Radiol Jan ;27(3):250-4.

Spinal arteriovenous metameric syndrome (SAMS), also known as Cobb syndrome, is a rare embryonic metameric syndrome, in which cutaneous, muscular, and or bony vascular lesions as well as para spinal and or spinal vascular lesions are found in the same metamere. Less than 80 cases with this syndrome have been reported in the literature and only one case was reported from Indian subcontinent. Classically, a birthmark (a cutaneous venocapillary malformation) and a spinal lesion (arteriovenous malformation or arteriovenous fistula) are found in the same or neighboring metameres. It should alert the physician and radiologist for early imaging of spine as early diagnosis and timely intervention would be favorable and may save patient from permanent neurological sequelae.

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