Shoaib Ahmed Qureshi, Muhammad Iqbal Khan, Riffat Arbab, Mehmood Badini, Maria Mehmood, Aisha Arshad, Warda Lodhi, Hafsa Jaffar.
Outcomes of Primary Repair in Typhoid Perforation.
Ann Pak Inst Med Sci Jan ;13(4):296-300.

Objective: To determine the outcomes of primary repair in patients with typhoid perforation. Study Design: Case series study Study Duration: Study was conducted for 3 year from 15th January 2014 to 15th January 2017. Methodology: 280 Patients presenting to the emergency department were included according to the inclusion and exclusion criteria via nonprobability consecutive sampling. Written informed consent was taken. The surgical procedure was performed by a senior surgeon having experience of more than 5 years. Postoperatively patient was followed up for ten days and final outcomes (wound infection, anastomotic leakage, wound dehiscence and intra-abdominal collection were assessed clinically and by ultrasound abdomen and was recorded on prescribed Performa. Data was entered and analyzed by using SPSS version 17 Results: The age range was from 15 to 50 years (average age of 25.9 + 9.87 years). Out 280 patients, 108(38.6%) were male and 172 (61.1%) were female. Intraabdominal collection occurred in 18(6.4%), wound dehiscence in 14(5%), wound infection in 74(26.4%) and anastomotic leakage in 12(4.3%). Conclusion: The primary repair of perforation is the treatment of choice for typhoid perforation. Early surgery and adequate resuscitation is necessary for successful management of patients with typhoid perforation.

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