Farooq Azam, Mian Iftikhar-ul Haq, Muhammad Tariq Safi.
Transnasal trasnssphenoidal surgery for pituitary tumours.
Pak J Neuro Surg Jan ;15(2):79-82.

Objective: To determine the frequency of early post-operatively complications of transnasal transsphenoidal surgery for pituitary adenoma.Study design: Descriptive study.Place and Duration of Study: Pak International Medical Science Khyber Pakhtoonkhawa from 1st February 2008 to 31st July 2011.Material and methods: A total 41 patients with pituitary adenoma fulfilling the inclusion and exclusion criteria were included in this study. All patients were undergone transnasal transsphenoidal surgery. These patients were followed up for early complications of transsphenoidal surgery for one month.Results: Out of 41 patients, there were 23 (56.09%) males and 18 (43.9%) females. The age of patients ranged from 10 to 70 years. In this study the overall mean age was 44.75 years. Majority of patients fourteen (34.14%) were in the age range of 41 – 50 years, followed by eleven (26.8%) patients in age group of 31 – 40 years, seven (17.07%) patients were in the age range of 51 – 60 years, five (12.1%) in the age range of 61 – 70 years, three (7.31%) in the age group of 21 – 30 years and one (2.4%) in the age group of 10 – 20 years. Early post-operative complications were diabetes insipidus in four (7.31%) patients, CSF leak two (4.87%) patients, meningitis in one (2.43%) patient and epistaxis in one (2.43%) patient.Conclusions: Surgical complications of Transnasal transsphenoidal surgery are minimal. Transnasal trans-sphenoidal surgery is a safe and effective treatment for pituitary tumour.

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