Ameet Lalwani, Waseem Mehmood Nizamani, Ameet Jesrani, Mahvesh Mahmud, Nida Hussain.
Diagnostic Accuracy of High Resolution Color Doppler Ultrasound (CDUS) in Detection of Perigraft Collections in Symptomatic patients Within 3 Months of Renal Transplant.
Pak J Radiol Jan ;25(4):142-8.

Objective: To determine the diagnostic accuracy of high resolution color doppler ultrasound (CDUS) in detection of perigraft collections in symptomatic patients within 3 months of renal transplant. Subjects and Methods: Total 173 patients of either gender with age 18 to 50 years, fulfilled inclusion criteria were registered in this study at the Department of Radiology Sindh Institute of Urology and Transplantation (SIUT), Karachi. CDUS was performed on Toshiba AplioTM 500 and GE VolusonTM 730 PRO using 3.75 MHz convex probe abdominally, serial longitudinal and transverse images were taken and assessed. It was followed by aspiration/drainage of the perigraft fluid collection. Results: In this study, there were 100 male and 73 female patients. The overall mean age was 36.72±8.94 years with range 32(18?50) years. The overall mean duration after transplantation was 48.21±16.28 days with range 67 (21 ? 88) days. Among total 173 study subjects, perigraft fluid collection was detected through CDUS in 100 patients, perigraft fluid collection drainage was found in 93 patients. Our results showed that 84 patients were true positive and 64 patients were true negative. Sensitivity, Specificity, PPV, NPV and accuracy were 90.3%, 80.0%, 84.0%, 87.7%, and 85.5% respectively. Conclusion: Imaging has a critical role in the evaluation of complications after renal transplantation. US and CDUS can facilitate prompt and accurate diagnosis of perigraft fluid collections.

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