Muhammed Tayyib, Hanif Mengal, Tahira Tasneem, Allah Ditta, Muhammed Farooq, Na Chaudhry.
Fibrinogen degradation products and D-Dimer study in patients with Pre-Eclampsia.
Pak Postgrad Med J Jan ;14(1):10-3.

A study of forty diagnosed cases of pre-eclampsia and twenty controls were carried out in Department of Pathology, PGMI, Lahore. In the present study coagulation profile and liver function tests were performed in the pre-eclamptic cases to see whether some tests could be used to predict coagulopathy in such cases. The study showed that prothrombin time, activated partial thromboplastin time and liver function tests were normal in all the cases. The haemoglobin level and platelet count were low while ESR was high in pre-eclamptic cases when compared with normal control pregnant women. The F.D.P’s and D dimmer were raised in most of the cases of pre-eclampsia especially those with severe pre-eclampsia. It was also concluded that D dimmer test is more sensitive as compared to F.D.Ps.

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