Umer Khan Orakzai, Nazullah, Fahad Ghayyour.
Incidence, Risk factors & Correlation of Early Rise of IOP with Visual Outcome in Post Diabetic Vitrectomy.
Ophthalmol Update Jan ;16(4):850-3.

Objective: To determine incidence, risk factors and the correlation of early rise of intraocular pressure (IOP) and visual outcome following pars plana vitrectomy (PPV) for proliferative diabetic retinopathy (PDR). Materials and Methods: A prospective longitudinal study conducted in Khyber Medical Center Dabgari Garden Peshawar carried from 1st July to 30 December 2017.The sample size was 74, they were having proliferative diabetic retinopathy and underwent Pars Plana Viterctomy (52 males and 22 females) The intraocular pressure and the best corrected visual acuity (BCVA) were recorded on day 1, week 1 and months 1, 3 and 6. The cross-tabulation and the t-test were used to evaluate the risk factors for early increase in IOP, defined as IOP >= 30 mmHg on day 1. The results were analyzed by different statistical tests using SPSS version 20. Results: The mean IOP on day 1 was 21.9 +- 9.9 mmHg with 15 cases (20.6%) with an early increase in IOP. The risk factors showed a significant association of the early increase of the IOP and the intra-operative elimination of the fibro-vascular frond (P = 0.004), the removal of the lens (P = 0.044) and intra-operative vitreous bleeding (P = 0.009). In the first three consecutive follow-up visits, the early increase in IOP was also associated with a consistently high IOP (P = 0.04), defined as an IOP> 21 mmHg. In addition, the difference in BCVA at 6 months between the two groups, that is, with and without an early increase in IOP was statistically significant (3.12 +- 1.53 logMAR vs. 2.12 +- 1.50 logMAR). , p = 0.026). Conclusion: The visual outcome is significantly compromised with an early increase in IOP of patients undergoing diabetic vitrectomy.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com