Kirran Iqbal, Maham Babar, Sumairatauseef, Rahat Akhtar.
Outcome of use of High Quality Chamomile Extract on Sleep Disorders Occurring after Menopause.
Ophthalmol Update Jan ;16(3):766-9.

Objective:To compare the outcome of four weeks use of high grade extract of Chamomile and the placebo on sleep disorder.It was a randomized controlled clinical trialat the Gynecology outdoor, Nishtar Hospital Multan and Bahawal Victoria Hospital Bahawalpur, from January 22, 2016 to January 10, 2018. Methodology: Two equal groups were made with 53 menopausal women in each aging at menarche and menopause and BMI was compared between the two groups. Sleep latency, time and number of awakenings, total sleep time, sleep quality, sleep efficiency, PQSI score, BDI, FSS and STAI-T score were compared between both the groups at baseline and 28th day. Student t-test was applied using SPSS v.23 computer software. P>0.05 was considered statistically insignificant. Results:After 4 weeks of treatment, significant improvement was observed in sleep latency, time of waking after sleep onset, number of awakenings and total sleep time in the Chamomile group compared with placebo group (0.023, 0.002, 0.019 and <0.001, respectively). The improvement in STAI score was statistically significant (0.024) in the chamomile group. There was some improvement observed in the chamomile group in terms of sleep quality (0.075) and sleep efficiency (0.059) but the differences were still statistically insignificant. Conclusion: It is concluded that chamomile extract has significant beneficial effects on the menopausal women suffering from sleep disorders.

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