Ahmad Hasan Alizai, Adnan A Saleem, Inayatullah Khan, Mohamud Walid Peerbux.
Comparison of Intra-lesional Triamcinolone Acetonide Injection with Incision & Curettage in the Treatment of Primary Chalazion.
Ophthalmol Update Jan ;16(2):631-5.

Background: Chalazion is a frequently presenting eyelid pathology which merits further refinement in treatment protocols. Objective: To compare an injection of intralesional triamcinolone acetonide and incision & curettage in terms of frequency of regression of the lesion. Subjects and Methods: This randomized controlled trial was done in Al-Shifa Trust Eye Hospital, Rawalpindi during seven months. One hundred and eighty (n=180) patients aged between 14-50 years irrespective of gender who had a palpable chalazion on any eyelid for > 4 weeks with normal eyelid anatomy were studied. Patients were equally divided into two groups. Group A were treated with intralesional TA and Group B treated with I&C. Frequency of regression was measured at 4 weeks after intervention in both groups and compared using Chi-Square test. Results: In group A, 77.8% (n=70) of lesions were regressed while in group B the percentage was 82.2% (n=74). Regression rate was not found to be significantly different among both groups (P > 0.05). Gender, age groups and different location of the lesions wise stratification showed no difference in both groups (P > 0.05). Conclusion: The results suggest that a single transconjunctival 0.2 mL injection of 10 mg/mL of TA has efficacy comparable with I&C in the treatment of chalazian with less patient`s inconvenience.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com