Maria Sultan, Syed Amir Hamza, Umer Khan.
Efficacy of Nepafenac 0.1% VS Topical Ketorolac 0.5% in Phacoemulsification Surgery in terms of Maintaining Pupil Dilatation.
Ophthalmol Update Jan ;15(2):119-21.

Objective: To compare topical ketorolac (0.5%) versus nepafenac (0.1%)in phacoemulsification surgery in terms of maintaining pupil dilation. Materials and Methods: In this study sample size was 250 eyes in each group. All patients in age range of 45-75 years including both genders, having age related cataract with round, regular and reactive pupil. A detailed history and complete examination was done including slit lamp examination, fundoscopy and checking for pupillary reaction. Patients in group A received topical nepafenac 0.1% while patients in group B received topical ketorolac 0.5%. Pupil diameter of each patient was measured with a caliper in the pre-operative and post-operative time. Results: In this study mean age in nepafenac group was 60 years with standard deviation � 12.73, while mean age in ketorolac group was 62 years with standard deviation � 11.92.In nepafenac group 150(60%) patients were male and 100(40%) patients were female while in ketorolac group 155(62%) patients were male and 95(38%) patients were female. Our study shows that nepafenac 0.1% was effective in 200 (80%) patients while ketorolac 0.5% was effective in 165 (66%) patients. Conclusion: Our study concludes that nepafenac 0.1% is more effective than ketorolac 0.5% in maintenance of dilated pupil during phacoemulsification surgery.

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