Zahir Gul, Muhammad Adnan, Adnan Liaqat.
Incidence of Raised of Intra Ocular Pressure amongst Non Glaucomatous patients after Yag Capsulotomy (A randomized controlled trial).
Ophthalmol Update Jan ;15(2):100-3.

Background: Raised IOP is most common and transient complication following Nd:YAG laser capsulotomy. An incidence of high IOP level more than 10mmHg was observed among 15-67% of eyes. Aim: To compare IOP elevation in non glaucomatous patients after YAG capsulotomy using NSAIDS (Non Steroid Anti Inflammatory Drugs) plus pressure lowering drugs versus NSAIDS alone. Methods: The study was a randomized controlled trial (RCT) and conducted in Department of Ophthalmology, Pakistan Institute of Medical Sciences (PIMS), Islamabad. The study duration was 6 months (August 2014-January 2015). A sample size of 80 was studied using WHO formula. One group (interventional group) is given NSAIDS plus pressure lowering drugs while the other group (placebo) is given NSAIDS alone. Chi square test was applied to observe the association between different variables. Results: The study includes 80 participants with 1:1 in both groups. There were 25 (62%) females and 15(38%) males in interventional group and in placebo group there were 20(50%) females and 20(50%) males in placebo group. There was no significant difference in mean visual acuity of two groups (P=0.209, P= 0.887 respectively). There was no statistically significant difference in IOP level of interventional and placebo group (P=0.456, P=0.559 respectively) Conclusion: There is no statistically significant difference in IOP reduction after YAG capsulotomy in non glaucomatous patients who were given NSAIDS plus pressure lowering drugs versus NSAIDS alone. No significant glaucomatous change was found among patients following YAG capsulotomy. Therefore in the absence of glaucomatous risk factors, NSAIDS can be prescribed, with close follow up after YAG capsulotomy.

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