Muhammad Kashif, Shua Azam, Humaira Ramzan, Afshan Hassan.
Association of ABO Blood Group with Glaucoma.
Ophthalmol Update Jan ;15(2):97-9.

Purpose: The purpose of this study was to determine any association of glaucoma (primary open-angle glaucoma (POAG), and Pseudo-exfoliative glaucoma (PEXG) with ABO blood groups. Aims and Objectives: i)To determine association between blood groups and glaucoma. ii) To identify ABO blood group as risk factor for POAG and PEXG. Material and Methods: In this case control study Hema-glutination patterns were used to determine the prevalence of the ABO blood groups in all the subjects. Odds ratio was calculated for each blood group. Patients having POAG and PEXG in age group 40 and above were included. Controls were selected from the relatives of the patients with the same age. Results: In the present study, the percentage of blood groups A, B, AB, and O in patients was found to be 17.85%, 46.42%, 21.42% and 14.28%, and in the control group, the values were 39.28%, 21.42%, 10.71%, and 28.57%,respectively. Odds ratio for blood group B was 4.5 in PEXG and for POAG it was 2.66. Similarly odds ratio for blood group AB was 2.9 in POAG and 1 in PEXG. Conclusions: In the present study group B was associated with both type of glaucoma and AB blood group was only associated with POAG.

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