Zia-ul Islam, Mohammad Arif.
Clinical Presentation in Retinoblastoma.
Ophthalmol Update Jan ;15(2):68-70.

Background: Retinoblastoma is the most common childhood malignancy of the eye. It has become one of the most curable paediatric tumor. Early diagnosis and treatment can stop the disastrous outcomes, in terms of sight and life. Objective: To determine the trends in demography and presentation of retinoblastoma children, in NWFP Pakistan & Afghanistan. Study Design: Prospective study Place of study: Referral center for retinoblastoma, Eye "A" Unit, Department of Ophthalmology, Khyber Teaching Hospital, Peshawar KPK, Duration of study: 31st January, 2007 to 1st January, 2009. Materials and Methods: Patients were registered and admitted in eye ward for evaluation, who presented with leukocoria and other related features suspecting retinoblastoma. EUA, C.T Scan, and ophthalmic scan was done to confirm diagnosis and document details. Face photographs and data were put on record. Results: 25 paediatric patients, who presented with clinical features of retinoblastoma were registered; 16 patients were male, 09 were female. Mean age was 0.5-7 years. 23 were from lower socio-economic group. 05 patient after diagnosis lost follow up, 20 children received full treatment and have regular follow up. 07 patients developed metastasis and one died. Conclusion: Meticulous understanding of features of retinoblastoma and acquiring skill to diagnose as well as treat retinoblastoma at first sight, increases survival and prevents loss of vision.

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