Adnan Thabit, Samiha Aleryani, Ahmed Alansy, Aziz Shaher, Tawfik Al Khatib.
Prevalence of Diabetic Retinopathy in Type: 2 Diabetic patients using Insulin vs those using oral Hypoglycemic Agent.
Ophthalmol Update Jan ;15(1):11-4.

Aim : to compare the prevalence and characteristics of diabetic retinopathy (DR) among type 2 diabetic Yemeni patients of more than10 years duration of diabetese mellitus(DM) using oral hypoglycemic agents(OHA) versus those using insulin for more than 10 years. Method : 300 type 2 diabetic patients were included in this study, 150 using OHA and 150 using insulin for more than 10 years and they underwent eye examination of anterior and posterior eye segments by slit lamp biomicroscopy and ophthalmoscopy. Fluorescein angiography and OCT were done when required. Also demographic characteristic and medical history were determined. Results : 300 patient with type 2 DM of more than 10 years duration were included in this study, 150 patients using OHA and 150 patients using insulin therapy for more than 10 years. 124 were female and 178 were male. DR was found in 152 patients (50.7% ). DR was seen in 105(70%) patients of 150 patients using OHA and in 47(31.3%) patients of 150 patients using insulin for more than 10 years . The prevalence of DR was higher in patients using OHA as compared to those using insulin. This differences was found to be statistically significant (p= ?0.0005) . Conclusion: This study demonstrated a significantly high prevalence of DR in Yemeni type 2 diabetic patients using oral hypoglycemic agents as compared to those using insulin therapy.

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