Tallat Najeeb, Muhammad Ajmal, Wajahat Ullah Khan Bangash.
Role of Intra-tympanic Steroid in the treatment of Sudden Sensorineural Hearing Loss (SSNHL).
Ophthalmol Update Jan ;14(4):185-8.

Objective: It was to compare the treatment results of oral and intra-tympanic steroids in the management of sudden sensorineural hearing loss (SSNH) and to find out the effectiveness of intra-tympanic steroids in sudden sensorineural hearing loss. Study Design: Randomized control trial. Place & Duration of Study: Conducted at Holy Family Hospital and Social Security Hospital from Dec 2008 to Dec 2013. Material & Method: All Patients were selected randomly with complaint of hearing loss for at least 3 days duration. PTA (pure tone audiometry) was advised to confirm SSNH. Patients were divided into Group A included patients who received oral steroid therapy dexamethasone 1mg/Kg body weight for three week and Group B included patients who received intra tympanic steroid injections, 1cc(4mg) of dexamethasone, every 7th day for 3 weeks. Any improvement in PTA of more than 20dB was considered significant. Follow up of patients was done for 6 months. Statistical evaluation of results was done by using window SPSS 16. Results: Total number of patients were 30, divided into Group A and B. In Group A, total improvement in one month was seen in 9 out of 15 patients (60%). In Group B, total improvement was seen in 11 out of 15 patients (73.3%). Results were significant as p value was <.05. Conclusion: Treatment should be started with oral steroids as early as possible; if the response to oral steroid is poor then intra tympanic steroid injections should be used as salvage therapy.

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