Roheena Wadud, Mran Khan M Kamran, Laiba Ajmal, Adeel Ajmal.
Effect of Single Intravenous Dose of Dexamethasone in Children undergoing Tonsillectomy/Adeno-tonsillectomy.
Ophthalmol Update Jan ;14(4):166-9.

Objective: To find the effect of single intravenous dose of dexamethasone in children undergoing tonsillectomy or adenotonsillectomy. Material & Methods: This comparative study was conducted in the department of Anaesthesia LRH/MTI Lady Reading Hospital Peshawar from May 2015 to Oct 2015, children of both gender, age 5-12 years, undergoing tonsillectomy were divided into two groups of 50 each, one group D was selected to receive dexamethasone 0.5mg/kg (maximum 8mg), the second group C was given equivalent volume of saline, at the time of induction of anaesthesia. All the patients were observed in recovery and then in ward for post operative nausea and vomiting and also for need of anti-emetics for 24 hours. Results: The frequency of nausea and vomiting was significantly less in dexamethasone group D P<0.05, as compared with control group C. The need for rescue antiemetic was also significantly less in group D as compared to group C. Chi square test was applied. P<.05, which was considered significant. Conclusion: Single dose of dexamethasone, given at the time of induction of anaesthesia, reduces the frequency of postoperative nausea and vomiting in children and the need for rescue anti-emetics in the first 24 hours.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com