Muhammad Tariq Khan, Imran Ahmad, Jehan Zeb Khan, Mubashir Rehman, Zeeshan Tahir.
Comparison of Bevacizumab alone and combination of Bevacizumab with focal Application of Laser for the Treatment of Diabetic Macular Edema.
Ophthalmol Update Jan ;14(3):9-11.

Purpose: To compare the efficacy of intravitreal Bevacizumab alone with bevacizumab and focal macular laser for the treatment of diabetic macular edema. Material & Methods: It was a retrospective study conducted in Khyber Institute of Ophthalmic Medical Sciences (KIOMS), Hayatabad Medical Complex, Peshawar from March 2015 to August 2015. Results: A total of 146 eyes were included in the study with 60.96% male and 39.04% female patients with a mean age of 62.36 years.In 146 eyes focal macular edema was found in 46 patients (31.50%), diffuse in 53 (36.30%), cystoid in 23 (15.75%), and mixed types of macular edema in 24 patients (16.66%).Statistically significant difference was noted in macular thickness improvement and visual acuity from baseline after 6 months of treatment in both groups (p<0.005) but there was no significant difference between the bevacizumab alone group and in combination group of bevacizumab with focal laser in terms of effectiveness (0.64). Conclusion: There is no significant difference between intravitreal bevacizumab alone and combination treatment of bevacizumab with focal application of laser in the treatment of diabetic macular edema.

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