Saima Shahbaz, Shahbaz Mujtaba Ghauri, Samina Shaheen, Attiya Mubarak, Anjum Nasim Sabri.
Histomorphological Changes in Hypertrophied Tonsils in Children.
Pak J Med Health Sci Jan ;8(3):510-4.

Aim: To study histomorphological changes in hypertrophied tonsils in children and to co-relate the extent of these changes to the tonsillar hypertrophy Methods: Enlarged tonsils from thirty children with obstructive airway symptoms were obtained after tonsillectomy. Normal tonsils were obtained from 10 children’s at autopsy Results: In hypertrophied tonsils size, weight, epithelium and lymphoid compartment, all were affected. It was observed that there was an increase in thickness and keratinization of epithelium, increase in size of germinal centers, decrease in no of lymphoid follicles due to increase in size. Conclusion: Hypertrophic changes are probably immunological response to exposure to different antigens in an exaggerated manner and obstructive symptoms may lead to complications, sometimes fatal. Measures should be devised to prevent or treat tonsillar hypertrophy.

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