Sadia Latif, Saba Yasmin Usmani, Naheed Fatima.
Comparison of Sublingual and Vaginal Routes of Misoprostol in Termination of First Trimester Missed Abortion.
Pak J Med Health Sci Jan ;8(2):434-7.

Aim: To compare the sublingual and vaginal routes of misoprostol in termination of first trimester missed abortion. Methodology: The study was carried out in the Obstetrics & Gynecology unit-II of Bahawal Victoria Hospital Bahawalpur, Pakistan, having yearly turnover > 3000 indoor patients. Results: In vaginal misoprostol group 66.7% cases completely aborted while in sublingual group 73.3% expelled successfully (P=.831). In cases with gestational age upto 9 weeks complete abortion was seen 95%, mean insertion to abortion interval for vaginal and sublingual groups were 13.55 and 13.1 hours respectively (P<0.678). Side effects profile was low especially in cases of vaginal group. Conclusion: Vaginal and sublingual misoprostol were found to have same success rate but former was found to have low side effect profile.

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