Hafiz Moeen-ud din, Shah Murad, Ajaz Fatima.
Placebo controlled study on Comparison of effects of Nigella Sativa and Nicotinic Acid along with Low Fat Diet and Physical Exercise on LDL-Cholesterol and HDL-Cholesterol.
Pak J Med Health Sci Jan ;8(2):306-9.

To get good compliance of therapeutic goal of hypolipidemic agents by cardiologist and patient, some herbal drugs have had been used by some expert cardiologists. Among those herbal medicines Kalonji is most important drug used as hypolipidemic agent. In this research work hypolipidemic effects of kalonji are compared with hypolipidemic effects of Niacin. It was single blind placebo-controlled comparative study, conducted at Jinnah Hospital, Lahore from September 2013 to December 2013. Ninety hyperlipidemic patients were enrolled after written and well explained consent. Ninety patients were divided in three groups, one group as placebo and other two groups for Niacin and kalonji. After six weeks of therapy by 2 medicines, research proved highly significant changes in LDL-cholesterol, but significant changes in HDL-cholesterol in hyperlipidemic patients.

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