Raza Farrukh, Waseem Sadiq Awan, Makhdoom Ahmad Aziz Jillani.
Comparison of Recovery Characteristics of Sevoflurane and Isoflurane in Obese patients.
Pak J Med Health Sci Jan ;8(1):118-21.

Aim: To compare the recovery characteristics i.e.emergence time of sevoflurane and isoflurane in obese surgical patients. Study design: Randomized control trial. Place & Duration: Department of Anaesthesiolgy, DHQ hospital , Sargodha (Pakistan) and was completed in six months period from September 2012 to February 2013. Methods: Following informed consent,90 obese (BMI>30Kg/m2) patients were randomly divided into two groups.Group-A received sevofluane and Group –B received isoflurane for maintenance of anaesthesia following thiopentone induction. The speed of recovery was measured by time to eye opening,time to follow simple commands and time to correctly giving own names and current location. Results: The recovery time was faster in the sevoflurane group.Emergence time[mean time of eye opening (SD)=11.04+1.76 vs 13.04+1.82 min,Extubation time[mean time of sticking tongue out(SD)=13.00+1.55 vs 15.44+1.52 min] and orientation time[mean time of giving own name and current location(SD) =18.00+1.49 vs 20.13+1.45 min were much shorter in sevoflurane group as compared to isoflurane group. Conclusions: Sevoflurane provides more rapid recovery than isoflurane in obese surgical patients undergoing surgery of intermediate duration(1-2 hour).

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