Wasim Hayat Khan, Irfan Javed, Mubasher Farhan, Tehreem Fatima, Abdul Wadood, Awais Amjad Malik, Kamal H, Akhter N.
Effect of instilling 1 Liter normal saline into the peritoneal cavity after laparoscopic cholecystectomy on post-op pain relief: a randomized controlled trial.
Pak J Med Health Sci Jan ;7(4):1199-201.

Aim: To determine the pain relieving effect of 1litre intraperitoneal normal sline among patients undergoing laparoscopic cholecystectomy. Study design: It is a prospective randomized double blind study performed in surgical unit II of SIMS from March 2012 to Dec 2012. The 70 (48 female and 22male) patients included in the study who underwent Laparoscopic cholecystectomy were randomly divided into two groups (35 patients in control Group A; given local analgesia with Bupivacain only. 35 patients in group B Experimental Group B; given local analgesia with Bupivacain plus infiltration of 1litre normal saline intraperitoneally). Postoperatively patients of each group were evaluated for pain relief according to VAS. Results: In 24 female patients belonging to control group A (who were given local analgesia at port site with Bupivacain only) the average pain score was 7-8 whereas in 11 male of same group A, the average pain score was 6-7, whereas In 24 females patients belonging to experimental group B (who were given local analgesia at port site with Bupivacain as well as infiltered 1liter normal saline) the average pain score was 4-5, whereas 11 males of this group has average pain score of 3-4 Conclusion: Post operative intraperitoneal infiltration of 1 litre normal saline provides effective pain relief in patients who underwent elective Laparoscopic cholecystectomy for cholelithiasis.

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