Abdullah Khilji, Syed Meesam Iftikhar Rizvi.
Comparison of Morphological Changes in Placentae from Pre-Eclamptic Pregnancies and Normal Pregnancies.
Pak J Med Health Sci Jan ;7(4):962-5.

Aim: To assess the morphology of placenta from mothers having pre-eclampsia and to correlate with those from normal pregnancies. Study design: Study type; Prospective study Research design: Case Control study Place of study: Department of Anatomy, Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Centre (JPMC), Karachi. Methods: Total of 50 placentae were collected, divided into two groups, Control (Group A) and Pre-eclamptic (Group B) groups. Each group consisted of 25 placentae. All the placentae were observed for morphological features. Results: In this study, shape of placenta showed no changes in both pre-eclamptic and control groups. Pre-eclamptic placentae showed a highly significant decrease (P<0.001) in weight, diameter, thickness and number of cotyledons as compared to normal placentae. Conclusion: The present study concluded that pre-eclampsia is associated with remarkable morphological changes in the placentae.

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