Aamir Mahmood Ijaz, Syed M Naqvi, Raza Iqbal, Dogar H.
Relationship of Myasthenia Gravis with Thymic Pathology.
Pak J Med Health Sci Jan ;7(4):867-9.

Aim: To study the relationship of Myasthenia Gravis with different Thymic Pathologies. Methods: This descriptive study was performed at the Department of Thoracic Surgery, Mayo Hospital, Lahore between January 2010 and January 2012. A total of 60 consecutive cases of Myasthenia Gravis aged 15 and above were included in this study. Results: Out of 60 cases included in this study, 41(68.3%) were females. Based on Thymic Pathologies, 52(86.7%) cases were found to have Thymic hyperplasia while 8(13.3%) cases had Thymoma. Of the 60 cases included in this study, 54(90.0%) had features suggestive of Myasthenia gravis whereas 6(10.0%) had no such evidence. Conclusion: In conclusion it was observed that there is a strong relationship of Myasthenia Gravis with thymic pathology, with Thymic hyperplasia accounting for a greater majority of cases than Thymoma. Moreover, a significant female predominance is observed when both thymic hyperplasia and thymoma are collectively taken into consideration as one of the likely causes of Myasthenia Gravis.

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