Muaz Bin Sajjad, Muhammad Imran Sohail, Ghulam Mujtaba Nasir, Juwayria Omar, Haroon Rashid Khan, Saba Sohail.
Impact of Vitamin D3 Supplementation on Overweight and Obese Individuals.
Ann Pak Inst Med Sci Jan ;14(3):239-44.

Objective: To determine the effect of Vitamin D3 supplementation on overweight and obese individuals Methodology: This descriptive Cross Sectional Study was done. The participants in the study were selected from medical outpatient departments of three public sector hospital of Islamabad and Rawalpindi, from January to June 2018. All overweight of obese patients were randomly divided into two equal groups of 88 participants in each group, by random number table method. Group A was an intervention group who were given vitamin D3 and Group B, was given placebo. Vitamin D3 (dose) supplementation was given for 12 weeks. Anthropometric parameters including BMI, waist circumference, and waist to hip ratio was recorded at the start of the study and was noted on a predesigned performa. After completion of treatment repeat serum Vit. D3 level and anthropometric measurements were done. Results: The mean age in vitamin D group was 38.46 ±7.28 years and in placebo group 37.85±8.25 years. There was insignificant (p-value > 0.05) difference in body weight (76.56±11.25 vs. 75.85±10.76) before and after intervention among participants of vitamin D group. The comparison of waist circumference (92.78±7.35 vs. 92.24±7.21) and hip circumference (107.74±7.45 vs. 106.45±7.12) showed no any significant (p-value > 0.05) change after the intervention. There was a minor change in BMI on baseline 29.65±3.26 and after three months of intervention 29.38±3.1 kg/m2 but this difference was not statistically significant (p-value > 0.05). Conclusion: The supplementation with vitamin D3 during 12 weeks did not improve the anthropometric parameters like body weight, waist and hip circumference and BMI. So the correction of serum vitamin D3 level does not help in decreasing the anthropometric parameters.

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