Attique-ur Rehman, Waseem Ashen Malik, Syed Rizwan Hussain, Muhammad Ali Yaseen, Mn Tabassum, Mamoona Waseem.
Modes of Presentation of Multiple Sclerosis.
Pak J Med Health Sci Jan ;7(3):761-5.

Aims: To describe different modes of presentation of multiple sclerosis in the Pakistani population and to demonstrate that multiple sclerosis may present with a wide variety of signs and symptoms. Methods: This descriptive one time observational study was conducted in medical and neurology wards of Mayo Hospital, Lahore. Patients and their relatives were selected for interview, based on convenient sampling. The data was collected on a specially designed proforma. Thirty patients were included in this study. All patients were evaluated through clinical examination, blood tests, CSF examination and MRI. The data was analyzed using SPSS version 8. Results: Mean age was 29.43 years. Up to 57% of the patients were female. Only 16% of patients presented for the first time, while the rest had history of previous episodes. Most of the patients had more than one symptom at presentation. Visual disturbance alone or along with other symptoms was the presentation in around 63% of patients. Another 80% of patients presented with weakness. Urinary incontinence occurred in 40% of patients. Cerebellar signs were present in 17% of patients. In 13% of the patients, multiple sclerosis manifested with paraesthesias. Conclusion: It is an established fact that with early treatment relapses can be delayed. In addition, multiple sclerosis is an entity that must be considered in the differential diagnosis if neurological symptoms cannot be explained by any other neurological disease.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com