Karim Shah Faizi, Ishfaq Ahmed, Hamad Ahmad.
Comparison of Early Versus Delayed Laparoscopic Cholecystectomy: Choosing the Best.
Pak J Med Health Sci Jan ;7(1):212-5.

Aims: To compare early and interval laparoscopic cholecystectomy for postoperative conversion rate to open cholecystectomy and complications. Study design: It was a multi center randomized controlled trial. Duration: From 1-1-2010 to 31-12-12011. Material and method: A total of 50 patients (25 in each group) with acute Cholecystitis from Surgical Operation theatre of at Surgical Units Nishtar Hospital Multan /Ali Shirazi Hospital Sahiwal / D.H.Q. Chiniot, selected for Laparoscopic Cholecystectomy were included in this study. Two Groups (A&B) were created, Group-A was allotted to the early cholecystectomy and Group-B was allocated to delayed cholecystectomy patients. Results: Majority of the patients i.e., 8(32%) in Group-A and 10(40%) in Group-B were recorded between 41-50 years of age, 11(44%) in Group-A and 15(60%) in Group-B were females patients, post operative complications of laparoscopic cholecystectomy in both groups reveal that in Group-A, Injury to the biliary tree was found in 24%(n=6), wound infection in 8(32%), haematoma in 4(16%) and seroma in 7(28%) while in Group-B, these values were found as Injury to the biliary in 17(68%), wound infection in 19(76%), haematoma in 10(40%) and seroma in 16(64%), which shows a significant difference in all complications while conversion to open cholecystectomy In Group-A was found in 4(16%) and 12(48%) in Group-B while 21(84%) in Group-A and 13(52%) in Group-B were not converted for O.C.. Conclusion: We conclude significantly higher advantages of early LC (under 72 hours from the onset of the symptoms) over delayed LC for AC regarding conversion rate, complications rate, and operative time. Early LC represents the optimal timing for AC treatment, the delays in AC treatment being unjustified, and generating lesser results.

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