Saira Mushtaq, Ghazala Irshad, Afshan Zareen Bilal.
Effect of Dried Ginger (Zingiber officinale) on Serum Proteins in Hyperlipidemic patients.
Pak J Med Health Sci Jan ;12(2):583-6.

Aim: To study the effect of dried ginger on serum proteins and to compare the pre and post interventional levels of serum proteins in hyperlipidemic patients. Method: It was a randomized, single-blind, placebo controlled study in which 100 hyperlipidemic subjects, 50 in treatment group & 50 in placebo group, participated. Baseline sampling of subjects, with ginger in diet, was done before administration of first dose. Ginger capsules and placebo were administered orally to therespective groups, for 30 days. Blood samples were collected next day after administration of the last dose. Tests for serum proteins were performed on samples. Data was reported as means +- SEM. Paired t-test was employed to compare means of pre and post intervention values. p value less than or equal to 0.05 was regarded as significant. Result: Serum Total Protein levels of hyperlipidemic patients in treatment group were not affected significantly ( p- value=0.720) whereas there was a significant increase (p-value=0.041) in Serum Albumin levels of hyperlipidemic patients in treatment group. However, in the placebo group, both the Serum Total Protein levels (p-value = 0.690) and Serum Albumin levels (p-value = 0.067) were not significantly changed. Conclusion: This finding shows that dried ginger powder in a dose of 3g/day has no effect on serum total plasma proteins, but serum albumin is significantly increased.

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