Sahar Mudassar, Mudassar Ali, Nazma Kiran, Hassan Mehmood Paracha, Maham Nayyar.
Prevalence and Antibiogram Profile of Uropathogens in a tertiary care hospital.
Pak J Med Health Sci Jan ;12(2):867-9.

Background: Urinary tract infection (UTI) is one of the most common health problems worldwide. The current study was undertaken in order to determine the prevalence of UTI among symptomatic patients that were admitted in a tertiary care hospital. The pathogens responsible for UTI were identified and their antibiotic sensitivity patterns were studied. Methods: Subjects with clinically suspected acute UTI were enrolled in the study and their mid stream urine samples were collected in sterile plastic containers which were completely labeled. Urine samples were plated onto the blood agar and Mac Conkey agar plates with the help of wire loop under sterile conditions . The inoculated plates were incubated at 37˚C for 24 – 48hrs. Organisms were identified and their antibiotic resistance patterns were checked using standard guidelines . Result: Total samples collected were 765, both from females and males in the age groups 5 to 55 and above. From the total, 251 [32.8%] samples showed positive results [significant bacteriuria]. Gram positive bacteria were responsible for 12.9% and Gram neg ative bacteria for 87.1% of positive cases of UTI. The most common bacteria causing UTI was E. coli (37.4%). We also studied the antibiotic susceptibility pattern of alluropathogens which were isolated . Most of the Gram negative bacteria were sensitive to imipenem. In Gram positive bacteria, maximum sensitivity was noted for vancomycin, teicoplanin and linezolid.

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